Growth And Its Measurement
Methods Of Measuring Growth
- Human growth is diffuse (→spread throughout)
- Adult is taller, larger from front to back, has larger organs than a child
- Growth: permanent increase in amount of organic matter
- Produces new cells and increases size of existing cells
- Somatotropin (→growth hormone) stimulates cell division, protein synthesis / released by anterior lobe of pituitary gland
- Monitored by standing height and body mass
- Development: physical, emotional, mental, social changes throughout live
Supine Length (unable to stand → infant's length)
- Infant is placed, on it's back, on a table
- Ankles are gently pulled to straighten infant's leg
- Length is measured from top of its head to base of its heels
Standing Height
- Person standing with their heels flat on the ground
- Horizontal bar is moved to touch the top of the person's head
Body Mass → Amount of Organic Matter [Dry Mass → Plants]
- Wet body mass (weight) in humans is an INDICATION of organic matter
- Includes food + H2O → method can be misleading
Absolute Growth and Growth Rate
- ABSOLUTE GROWTH: total growth / cumulative height of a person
- [GRAPH] Regular increase in size that levels out at ≈16 years
- GROWTH RATE: increase (in an appropriate feature) per unit time
- GROWTH RATE = (SIZE AT T2 - SIZE AT T1) / (T2-T1)
- Highest in the first year
- Decreases rapidly during the first 2 years
- Constant, low rate during childhood
- Females and males have similar height until ≈14 → growth spurt occurs
- later but greater in males than in females
- Therefore, male becomes taller than the female at ≈14
- Growth stops by the age of ≈18
Advantages and Disadvantages of Cross-Sectional Study
- Measures people of different ages
- Calculates mean of a population → Individual peaks tend to be smoothed out
- Generalised picture of growth (-) may not be related to one individual (-)
- Easy to perform during clinical investigation (+)
- Short-period of time measurement (+)
Longitudinal Study
- Measures same person at regular intervals over a long period of time
- Accurate picture of individual growth (+)
- Measurements taken at different times can be compared
- Not suitable for an investigation (-)
- People leaf study area/lose interest in being involved in investigation
- Migration/death
- Takes a long time to see a pattern/conclusion
Relatives rates of growth of tissues and organs from birth to adulthood
- [GRAPH] Different parts of the body grow at different rates
- Head and brain develop first → being ≈90% of its adult size by the age of 5
- Before growth of bones and muscles in limbs
- Thus, results in a change in body proportion
- Reproductive system develops latest → remains below ≈20% until puberty
- Lymphoid tissues (appendix, spleen, thymus gland) reach max size before puberty → size is
- reduced to its adult size after puberty → reduction in size caused by sex hormones
- Curve of the whole body is similar to an ABSOLUTE GROWTH GRAPH as height is an
- indicator of general body size
- Head and brain develop first → being ≈90% of its adult size by the age of 5
- Different growth rates result in changes in shape during embryological and post-natal growth
Puberty
Physical And Endocrine Changes Associated With Puberty
- Growth spurt occurs earlier in girls but is larger in boys
- Sex hormones (testosterone; oestrogen + progesterone) cause
- Development of internal reproductive organs and 2° sexual characteristics
- Increase activity of sweat and sebaceous glands
- Blocked sebaceous glands cause acne
- Changes the relative amounts of protein and fat
- Total body mass : body fat ratio is lower in boys than in girls
- Testosterone causes greater growth of muscles
- Oestrogen causes an accumulation of fat in the body
- Menstrual cycle in females relates to the proportion of fat to muscle
- Total body mass : body fat ratio is lower in boys than in girls
- Testosterone stimulates growth of cartilage in thorax, pectoral girdle → shoulders expand
- Oestrogen stimulates growth of cartilage in pelvic → hips expand
The Role Of Hormones In Controlling Early Growth
- Puberty begins with release of gonadotrophin releasing factor (GnRF) form hypothalamus
- GnRF stimulates pituitary gland to release gonadotrophin hormone
- Has a different name but is the same in (1) males and (2) females
- (1) Interstitial Cell Stimulating Hormone ICSH → stimulates testosterone production by interstitial cells between seminiferous tubules
- (2) FSH → stimulates egg-containing follicles in ovaries
- Travels in blood stream to gonads (→ovaries or testes)
- Causes gonads to release sex hormones
- Has a different name but is the same in (1) males and (2) females
- Internal stimuli must be involved to trigger initial release of GnRF
- Improved diets → faster grow of female, reach stage of maturity at younger age
- Age of menarche (→first period) is earlier than it was in the 19th century
- Relates to changes in female's muscle:fat ratio
- Girls with low body fat tend to have a later menarche
- Female athletes who have a high muscle:fat ratio
- Women who starve during anorexia nervosa find that their periods stop as they lose body fat
- Improved diets → faster grow of female, reach stage of maturity at younger age
Table 16-3-1: Summary of hormones controlling growth
Name of Hormone | Site of Release | Actions |
Somatotropin | Anterior pituitary gland | Stimulates mitosis, protein synthesis |
Thyroxine | Thyroid gland | Stimulates rate of metabolism |
Gonadotrophins | Anterior pituitary gland |
|
- FSH |
| - Development of follicle/egg cells and oestrogen secretion by follicle cells in ovaries |
- ICSH |
| - Spermatogenesis in testes |
- LH (females) |
| - Triggers ovulation, forms corpus luteum, thickens uterus lining, produces milk in breasts |
- LH (males) |
| - Secretion of testosterone by testes |
Oestrogen | Ovaries | - Growth of 2° sexual characteristics |
Progesterone | Corpus luteum | - Growth of breasts |
Testosterone | Testes | - Growth of 2° sexual characteristics |
Table 16-3-2: Changes associated with puberty
In Boys | In Girls | Hormonal Stimulation | In Boys | In Girls | |
Testes | Ovaries, Oviduct, | ICSH (boys) | Growth hormones | Testosterone | Oestrogen |
Body growth | Breasts |
| Growth hormones | Testosterone | Oestrogen + Progesterone |
Facial Hair, Larynx | Pelvic girdle |
|
| Testosterone | Oestrogen |
Pubic and axillary (underarm) hair | |||||
| First menstrual flow (menarche) |
|
|
| Oestrogen + Progesterone |
