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A2 Human Biology Unit 1


Text questions

P8/Q1   Because they control the same characteristics.
 
P9/Q2 a) Chromosomes become shorter and fatter; or
Nucleolus disintegrates; or
Nuclear envelope disintegrates
 
  b) In prophase of meiosis (I) homologous chromosomes pair up; (they don't in mitosis).
 
P10/Q3   Anaphase of meiosis (I)
 
P12/Q4   223
 
P13/Q5   The possible number of genetically different cells will be higher (possibly infinite).
 
P14/Q6 a) Haploid → possessing half of the normal/somatic number of chromosomes (23 for a human);
possessing a chromosome from each pair of homologous chromosomes.
 
  b) Homogametic producing gametes which have the same set of chromosomes
(eg. one X - sex chromosome, no Y chromosome).
 
P16/Q7   Dominant
 
P16/Q8   Both allelles (R-red, W-white) show up (codominance), (red + white = pink).
 
P18/Q9 a) When Io is paired up with any other allelle (eg Ib), then it is always «switched off», and the other allelle determines the antigen present (ie. : Ib).
 
  b) When IA and IB are paired up, they both determine the phenotype (antigen A & antigen B are both present on the plasma membrane of RBC).
 
P19/Q10 a) 3 : 1 (for monohybrid with dominance)
 
  b) 9 : 3 : 3 : 1 (dihybride with dominance)
 
P22/Q11   Father never passes chromosome X (locus of Xh is there) to his son!
 
P23/Q12 a) Individual 4 is a female, her son is a sufferer, so she must be a carrier (XHXh).
 
  b) Individual 10 is a female, only her father is a sufferer (his X chromosome is Xh), so she must have inherited Xh, hence she must be XHXh.
 


Assignment

P27/Q1  
  b b
B Bb Bb
b bb bb

P27/Q2

a)

Typica WTWT
Intermediate WTWR
Annulate WRWR
 
  b)
  WT WR
WT WTWT WTWR
WR WTWR WRWR

P28/Q3

a)

¯
Order of decreasing dominance
WB
WM
WAWC
WH
 
  b)
(i)
  WB WM
WB WBWB WBWM
WM WBWM WMWM
Bipunctata : melanopleura = 3 : 1
   
(ii)
  WA WH
WM WMWA WMWH
WH WAWH WHWH
Melanopleura : annectans humeralis = 2:1:1

 

Examinations

P28/Q1 a) (i) Meiosis → Reduction of number of chromosomes from 2n to n.

(ii) Mitosis → Number of chromosomes unchanged.

  b)
Feature Female offspring Male offspring
Crossing over v x
Independ. segreg. of chromosomes v x
Random fusion v x
 
c)

Males develop from unfertilised eggs → males inherit all genes from their mother as they are
 
P29/Q2 a) (i) XBXb

(ii) Because a male has only one X chromosome → there is only one allele (either XB or Xb).
Both XB and Xb are needed for the expression of tortoiseshell phenotype.
 

  b)
Phenotypes Black female Ginger male
Genotypes XbXb XBY
Gametes Xb Xb XB Y
Off. Genotypes XBX XBX XbY   XbY
% Tortoiseshell kittens 50%  

P30/Q3

a)

Male with normal sight (nn).
 
  b) Nn → she is a sufferer (so must have gene N). She is not a homozygote (NN) because some of her children are not sufferers → she must be a heterozygote then.
 
  c)
XNXn XnYn
XN Xn Xn Yn
XNXn XNYn XnXn XnYn
1/4 = 25%      
 

 

 

 

 

 

 
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