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A2 Human Biology Unit 13


Text questions

P270/Q1   The main ingredient of chocolate are lipids ("cocoa butter") and carbohydrates (sucrose). The same mass of toast consists mostly of starch. Starch is later digested into glucose. The number of glucose molecules is much larger than the number of glucose and fructose molecules from the hydrolysis of sucrose. Hence a more rapid rise in blood glucose concentration in the person who has eaten the toast.
 
P271/Q2 a) Alpha and beta cells in pancreas;
 
  b) Receptors activate effectors by secreting hormones into the bloodstream
(alpha cells - glucagon, beta cells - insulin);
 
  c) Enzymes (which convert glycogen to glucose or vice versa);
 


Assignment

P280-283   Follow instructions in the coursebook;


Examinations

P283/Q1 a) Temperature affects the rate of reaction. At a lower temperature: lower number of random collisions between substrate molecules. At a higher temperature: higher number of collisions between substrate molecules, but also, an increased amount of vibration of atoms present in the molecules of the enzyme. An increased temperature may lead to the enzyme being denatured. Hence maintaining optimum temperature for enzymatic action is crucial.

  b) Temperature of blood decreased → receptors in hypothalamus : heat conservation centre → vasoconstriction/ shivering/ raising of hair/ increased metabolic rate. Temperature of blood increased → receptors in hypothalamus : heat loss centre → hair lowered/ sweating/ vasodilation/ decreased metabolic rate.
 
  c) (i) Surface area/volume ratio small, hence less heat lost through radiation/ convection/ conduction.

(ii) Short, stocky body confers an advantage on the possessor of the characteristic, hence a higher chance of survival → higher chance of producing offspring → some offspring will have inherited alleles for short/stocky body → repetition of the cycle …
 

P284/Q2 a) (i) Glucose ingested & absorbed into the bloodstream → rise in blood glucose detected by beta cells in pancreas → increase in insulin secretion;

(ii) An increase in the concentration of glucose (initial cause) causes an increase in concentration of insulin . This increase in concentration of insulin causes decrease in the concentration of glucose (final effect).
 

  b) During strenous exercise glucose present in the blood is used by respiring muscles, consequently glucose level in blood drops → the drop is detected by alpha cells in pancreas → increase in glucagon secretion : activation of enzymes converting glycogen to glucose.
 
  c) Insulin affects only cells which have specific receptor molecules present in their cell membrane.
 
  d) Insulin molecules bind to receptors in the cell- surface membrane → chemical signal (enzymes) are activated → vesicles (made of phospholipid bilayer with glucose carrier proteins incorporated into it) move and fuse with the cell membrane. Glucose carrier proteins, which are now incorporated into the cell surface membrane, will allow glucose molecules to pass inside the cell by facilitated diffusion.
 
  e) Insulin activates enzymes which convert glucose into glycogen.
 
  f) (i) Insuficient insulin → insuficient uptake of glucose by cells → substrates other than glucose used up by cells for respiration (e.g.lipids), hence RQ below 1.

(ii) Strenous exercise : level of glucose in blood drops → glucagon produced → glycogen converted to glucose → glucose level increased. Therefore, as a result of a physical exercise the concentration of glucose in blood will increase. In healthy organisms, after exercise, this higher concentration of glucose is corrected by negative feedback (:increased glucose → increased insulin → decreased glucose). However, in diabetics the negative deedback doesn't function, therefore the concentration of glucose in blood remains high.

 

 

 

 

 

 

 
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