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A2 Human Biology Unit 2


Text questions

P34/Q1   Because of the sampling bias:
Is the probability of the quadrat landing at any point of the surveyed area the same?

This could depend on:

  • Your strength
  • Technique of throwing the quadrat
P35/Q2   Mean = 3.7
Median = 3.8
Mode = 3.8

The data do not follow a normal distribution because Mean (3.7) is different than Median (3.8) and Mode (3.8).
 

P36/Q3   Smaller standard deviation.
 
P37/Q4   Yes.
 
P38/Q5   AABB AABb AAbb AaBB AaBb Aabb aaBB aaBb aabb
 
P41/Q6   All the genes for a certain characteristics (eg. wing length) which are present in a given population.
 
P41/Q7   1 - 0.6 (L) = 0.4 (l)
 
P42/Q8   Hardy Weinberg principle predicts that the frequencies of the alleles of a particular gene in a particular population (i.e. values of p and q) will stay constant from generation to generation.
 
P43/Q9   Homozugous recessive genotypes will always express themselves in phenotypes (= q2)
 
P44/Q10   See the lower graph/curve.
 
P46/Q11   Directional selection.
 
P47/Q12   Better camouflage.
 
P48/Q13   Rate of respiration in organisms with sickle cell allele would be depressed by a reduced oxygen - carrying capacity of RBC. This could affect the organisms' chances of survival. « Fight or flight » situations often require high amounts of energy to be released in a short period of time. This requires a good supply of oxygen to the respiring tissues, which would not be possible due to reduced oxygen - carrying capacity of RBC.
 


Assignment

P50/Q1 a)
  b) Glutamate molecule has lost some atoms of H when new bonds have been created.
 
  c) The enzyme is responsible for the addition of a carboxyl group.
 
P50/Q2   Phospholipids are present in the biological/cell membranes. The ability of the residue to bind with blood cells can speed up the process of the formation of a blood clot.
 
P50/Q3 a) Carboxylase (which controls the synthesis of glutamate) only works in the presence of vit. K. Warfarin (competitive inhibitor of vit.K) inhibits the synthesis of glutamate. The R group of glutamate residue binds to phospholipids and in this way is speeding up the clot formation. If there is a lack of glutamate this process of clot formation will impaired.
 
  b) Large doses of vit. K will change the ratio between vit. K and warfarin molecules. As a result more vit. K molecules will be to molecules of carboxylase which control synthesis of glutamate.
 
P51/Q4 a) WsWs - advantage: small amounts of vit. K required in the diet.
 
  b) WsWr - advantage: resistant to warfarin, moderate amounts of vit. K required in the diet can be obtained in natural conditions.
 
P51/Q5 a)
Ws Wr  
WsWs WsWr Ws
WsWr WrWr Wr
 
  b)
Ws Wr  
WsWs WsWr Ws
WsWs WsWr Ws
 
P51/Q6   Offspring WsWr from Parental crosses WsWr x WsWs at the beginning had the advantage of resistance to warfarin and moderate requirements for vit. K in the diet. Offspring WsWs was selected against due to its low resistance to warfarin. Frequency of the genotype WsWr increased. Later Parental crossed WsWr x WsWr produced 50% WsWr genotypes (selected for) and 50% genotypes selected against (WsWs, WrWr). No further increase in the frequency of genotype WsWr followed.

P51/Q7   Genotypes with the dominant allele for warfarin resistance are not being selected for, because warfarin poisoning is extremely rare in the human population.
 


Examinations

P52/Q1 a)
      46      
  23       23  
23   23   23   23

  b)
  • Random/independent assortment of chromosomes (at anaphase I (→paternal and maternal chromosomes can be found in 223 various combinations in daughter cells).
  • Crossing over (→further increases recombination of DNA material in daughter cells).
  c) Genetic variation → one genetic variant confers an advantage on the possessor of a favourable allele of a gene the possessor of the favourable allele will have more offspring than the possessor of only the less favourable alleles favourable alleles will be passed onto some of the offspring → the frequency of this allele in the population will increase (i.e. natural selection has occurred).
 
P52/Q2 a)
Parental phenotypes Red   Black  
Parental genotypes Rr   rr  
Parental Gametes R r r r
Offspring genotypes Rr Rr rr rr
// phenotypes red red black black
 
  b)
(i)
  • q2 (rr) = 84/149 = 0.56
  • q = 40.56 = 0.75
  • p = 1 - q = 0.25
  • (Rr) = 2pq = 2 x 0.25 x 0.75 = 0.375 = 37.5%
(ii)
  • No genetic mutations occur
  • Random mating between individuals of the population.
P52/Q3 a)
  • Both parents are homozygotes
  • Both parents have the same form (allele) of the gene under investigation.
  b) Cob length: 24 - 26 cm
 
  c) (i) Polygenic inheritance: characteristics controlled by many genes located on the same or on different chromosomes.

(ii) Homozygotes (produced by pure breeding) both in variety A and variety B had cobs of different length (→there must be some other genes which modify phenotypes resulting from homozygous genotypes.) Similar observation can be made when analysing frequencies of phenotypes, which result from heterozygous genotypes of F1.
 

  d) (i) Both parental phenotypes demonstrate he differences in the cob length. This variation can
also be found in the offspring, so it is likely to be passed down in genes (inherited).

(ii) In spite of pure breeding variety A and variety B demonstrate variation which may result
from environmental factors.
 

  e) (i) Gene is a part of DNA present in a chromosome, which controls a certain characteristic/feature
of a living organism

(ii) An allele is a form of a gene. A gene must have at least 2 different alleles,
a dominant and a recessive one.
 

  f) (i) ww

(ii) Ww
 

  g) (i) 0.7 (W), 0.3 (w)

(ii) Frequency Ww = 2pq = 2 x 0.7 x 0.3 = 0.42 %Ww = 42%

 

 

 

 

 

 

 
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