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AS Human Biology Unit 7


Text questions

P119/Q1   Temperature affects the rate of enzyme controlled reactions. At a low temperature processes of metabolism in bacteria are slowed down, hence slower growth of bacterial cells.
 
P120/Q2   The pressure of air in the microbiology labs is below the atmospheric pressure → air (containing micro- organisms) from the lab will not move to the other parts of the building (due to negative pressure gradient).
 
P120/Q3   Done in the course-book.
 
P124/Q4   Haemocytometer is used in carrying out the total cell count =>all cells (dead and alive/viable) are counted, hence a higher number obtained. Serial dilutions and pouring plates are used in carrying out the viable cell count, hence a lower number obtained.
 
P126/Q5   Excessive use of antibiotics → resistant strains of Mycobacterium tuberculosis → number of infections caused by TB increased.
 
P127/Q6   ORT helps to replace the water lost through diarrhoea and vomiting.
 
P133/Q7   A higher possibility of entering a human body (human activities in fresh water reservoirs, e.g. lakes, usually occur during daytime).
 


Assignment

P139/Q1   Flagellate bacilli are rod-shaped bacteria with a flagellum/tail (used for locomotion).
 
P139/Q2 a) 7 mm
 
  b) 7 mm = 7000 micrometers
7000 micrometers / 2000 = 3.5 micrometers
 
P140/Q3 a) Ability of a micro-organism to cause a disease is called virulence. Virulence determinant is the ability of a micro-organism to produce toxins. P. aeruginosa produce toxins which break down proteins making up host's cells toxins destroy the host's cells.
 
  b) "Quorum sensing" refers to the critical density of the bacterial population which will cause the
concentration of messenger molecules around them to be high enough to trigger a change in their "behaviour"
(production of toxins).
 
  c) Number of cells per cm3
 
P140/Q4 a) Lag phase (1) (see fig 7.9 p.125)
 
  b) As fig 7.9 p.125
 
P140/Q5 a) Toxins not produced by the bacteria → no/reduced defensive reactions of the host organism → bacteria more likely to reproduce/multiply in numbers/colonise the tissues of the host.
 
  b) Toxins break down the proteins of the host's cells → products of the breakdown (e.g. amino-acids) can be used by the bacterium to synthesise its own organic molecules or/and cause irritation (→scratching → bacterial cells spread to unaffected areas).
 
P140/Q6   (Write you own summary)
 
P140/Q7   Production of toxins by the bacterium is triggered by an increased concentration of the messenger molecules. Therefore, a drug which breaks down (or binds with) the messenger substance will delay/cancel the moment when the production of these toxins is started.
 


Examinations

P141/Q1 a) Adult worms do not have access to oxygen present in the oxyhaemoglobin of the RBC in the human host/can use glucose present in the human blood as substrate for anaerobic respiration and produce ATP for growth/reproduction.
 
  b) Eggs are shed with urine/faeces into fresh water
→ fresh water has less negative WP
→ hatching of the eggs
 
  c) Cercaria in this way increase their chance of entering their human host (human's body temperature is higher than the temperature of water).
 
P141/Q2 a) (i) RNA carries a code for the structure of DNA which will be synthesized through the
process of reverse transcription (RT).

(ii) Reverse transcriptase - an enzyme, which controls the process of RT.
 

  b) Bacterium, which causes the type of pneumonia as well as the form of cancer mentioned in the question is normally recognised and dealt with by T-lymphocytes. The number of T-lymphocytes is reduced due to HIV infection, hence the onset of the diseases.
 
  c) Vaccines (inharmful strains of bacteria) trigger the process of acquiring active immunity (increased
resistance of the organism to the virus). Vaccine → memory lymphocyte. If the same strain of the virus
infects the organism, then: memory lymphocyte → rapid immunological response. If a different/mutated
strain of the virus caused infection, then memory cells do not recognise the virus → rapid immunological response will not occur.
 
P142/Q3 a) Total number of cells in the triple-lined square = #cells
Volume of suspension within the square: 0.2mm x 0.2mm x 0.1mm = 0.004mm3

#cells - 0.004mm3
?cells - 1.0mm3

Hence: ?cells = (1.0 x #cells) / (0.004)
 

  b) ?cells x 103
 
 

 

 

 

 

 

 
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