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MODULE 3 SECTION 12.5

Genetics


Multiple Choice Questions

Fill out the questions and click on "Submit" once you have finished.
This will mark your answers.
All answers have been provided by Ian White.

1. Electrophoresis is used to

(a) amplify small DNA samples to obtain enough for analysis
(b) clone genes
(c) match a gene with its function
(d) cut DNA into fragments
(e) separate fragments of DNA

2. DNA fingerprints used as evidence in a murder trial look something like supermarket bar codes. The pattern of bars in a DNA fingerprint shows

(a) the order of genes along particular chromosomes
(b) the presence of various-sized fragments of DNA
(c) the exact location of a specific gene in a genomic library
(d) the presence of dominant or recessive alleles for particular traits
(e) the order of bases in a particular gene

3. The immediate goal of the Human Genome Project was to

(a) Develop new technologies for studying DNA
(b) compare the genomes of a large number of individuals from different parts of the world
(c) map and sequence the genomes of important research organisms such as Drosophila sp.
(d) map all the human genes and determine the nucleotide sequence of the entire human genome
(e) find cures for human genetic disorders

4. The deoxyribose part in the name deoxyribonucleic acid refers to the

(a) rungs of the sugar ladder
(b) bonds that hold the two strands together
(c) sugar component of DNA
(d) type of helical arrangement
(e) a new type of oxygen-free blackcurrant drink

5. Which of the statements about electrophoresis is false?

(a) The process requires an electric current
(b) This technique can be used to separate charged molecules
(c) Large molecules migrate more slowly in the agarose gel than small molecules
(d) The technique can be used to easily separate nonpolar molecules.
(e) None of them.

6. A nucleotide of DNA could contain

(a) adenine, ribose, and phosphate
(b) nitrogenous base, phosphate, and glucose 
(c) phosphate, deoxyribose, and thymine
(d) uracil, deoxyribose and phosphate
(e) anything whatever – its 4,500 million years old, for goodness sake!

7. In recombinant DNA experiments,______ is used to cut pieces of DNA and ______ joins the resulting fragments to form recombinant DNA.

(a) a transposon . . . a restriction enzyme
(b) a transposon . . . a plasmid
(c) DNA ligase . . . a restriction enzyme
(d) a plasmid . . . DNA ligase
(e) a restriction enzyme . . . DNA ligase

8. The phosphate and sugar groups of a nucleotide are held together by

(a) ionic bonds
(b) covalent bonds
(c) Van der Waals forces
(d) hydrogen bonds
(e) James Bonds

9. The technology that Rosalind Franklin used that finally clarified the structure of DNA was

(a) autoradiography
(b) ultracentrifugation
(c) electron microscopy
(d) X-ray diffraction
(e) gel electrophoresis

10. Beadle and Tatum showed that each kind of mutant bread mould they studied lacked a specific enzyme. Their experiments demonstrated that

(a) cells need specific enzymes in order to function
(b) genes are made of DNA
(c) enzymes are required to repair damaged DNA information
(d) mutations are changes in genetic information
(e) genes carry information for making proteins

11. At one point as a cell carried out its day-to-day activities, the nucleotides GAT were paired with the nucleotides CUA. This pairing occurred

(a) when an mRNA codon paired with a tRNA anticodon
(b) during translation
(c) during transcription
(d) It is impossible to say, given this information
(e) in a double-stranded DNA molecule

12. The information carried by a DNA molecule is in

(a) the sugars and phosphates forming its backbone
(b) the total number of nucleotides it contains
(c) the order of the nucleotides in the molecule
(d) its amino acid sequence
(e) the RNA units that make up the molecule

13. Which are arranged in the correct order by size, from largest to smallest?

(a) chromosome - gene - nucleotide - codon
(b) chromosome - gene - codon - nucleotide
(c) codon - chromosome - gene - nucleotide
(d) nucleotide - chromosome - gene - codon
(e) gene - chromosome - codon – nucleotide

14. During translation, chain elongation continues until

(a) no amino acids are left
(b) all tRNAs are empty
(c) the polypeptide is long enough
(d) the ribosomes run off the end of mRNA
(e) chain terminator codons occur

15. Imagine an error occurring during DNA replication in a cell, so that where there is supposed to be a T in one of the genes there is instead a G. What effect will this probably have on the cell?

(a) The amino acid sequence of one of its kinds of protein will be completely changed
(b) Each of its kinds of protein will contain an incorrect amino acid
(c) One of its kinds of protein might contain an incorrect amino acid
(d) An amino acid will be missing from one of its kinds of protein
(e) An amino acid will be missing from each of its kinds of protein

16. A geneticist found that a particular mutation had no effect on the polypeptide encoded by a gene. This mutation probably involved

(a) deletion of the entire gene
(b) insertion of one nucleotide
(c) substitution of one nucleotide
(d) deletion of one nucleotide
(e) alteration of the start codon

17. During the process of translation (polypeptide synthesis), ________ matches an mRNA codon with the proper amino acid.

(a) DNA polymerase
(b) transfer RNA
(c) a ribosome
(d) messenger RNA
(e) GTP

18. Each nucleotide in a DNA molecule is composed of

(a) a nitrogenous base and a phosphate group
(b) a sugar called ribose, a nitrogenous base, and a phosphate group
(c) a sugar called deoxyribose, a nitrogenous base, and a phosphate group
(d) a sugar called deoxyribose and a phosphate group
(e) deoxyribose and a nitrogen base.

19. The bases on one strand of DNA are CTAGAAC. The complementary section on the other strand of DNA is

(a) CTAGAAC
(b) AGCTCCA
(c) GATCTTG
(d) TCGAGGT
(e) GUTCTTG

20. Covalent bonds between the nucleotides of new DNA strands are formed by enzymes called

(a) pyrimidines
(b) purines
(c) nucleotides
(d) transforming factors
(e) DNA polymerases

21. DNA replication occurs ensuring that all cells in a multicellular organism carry the same genetic information.

(a) in a few hours
(b) slowly
(c) before a cell divides
(d) after cell division ends
(e) whenever

22. Each gene minimally dictates the production of one

(a) chromosome
(b) codon
(c) tRNA
(d) DNA strand
(e) polypeptide

23. Transcription is the process of converting a sequence of DNA nucleotides into

(a) a single strand of RNA
(b) a double strand of RNA
(c) a single complementary helix of DNA
(d) protein
(e) polypeptides

24. The conversion of a sequence of RNA nucleotides into a sequence of amino acids is called

(a) transcription
(b) replication
(c) RNA splicing
(d) translation
(e) mutation

25. mRNA directs the building of proteins through a sequence of

(a) introns
(b) codons
(c) exons
(d) anticodons
(e) proteins

26. The RNA molecule used during transcription is

(a) transfer RNA
(b) ribosomal RNA
(c) transcription RNA
(d) messenger RNA
(e) polymerase RNA

27. The codons of mRNA are translated to amino acids by

(a) translation RNA
(b) transcription RNA
(c) transfer RNA
(d) messenger RNA
(e) ribosomal RNA

28. Any change in a nucleotide sequence of DNA is called

(a) mutagen
(b) replication
(c) duplication
(d) splicing
(e) mutation

29. Rejoining DNA fragments from two organisms is best known as

(a) conjugating DNA
(b) declining DNA
(c) mapping genes
(d) recombinant DNA technology
(e) gene sequencing

30. The gene-cutting tools of recombinant DNA technology are

(a) helicases
(b) DNA ligases
(c) DNA vectors
(d) plasmids
(e) restriction enzymes

31. The "one gene one protein " theory can be explained how genes control in cells by

(a) determining polypeptide chains
(b) interacting with proteins in the chromosomes
(c) assorting independently during meiosis
(d) inhibiting enzyme formation in some cell reactions
(e) replicating before the beginning mitosis

32. Point mutations

(a) remain in the parent and cannot be passed on to the offspring
(b) occur at the 5' end of a DNA strand
(c) forces the genetic code to be read from the wrong point
(d) are caused by a break in the chromosome
(e) result when one nucleotide is changed for another

Use the diagram of a technique in molecular biology and your knowledge of biology (you what?) to answer questions 33 to 35 (below):

33. The technique being used to assess this information is:

(a) human genome determination
(b) karyotyping
(c) transformation
(d) DNA blotting
(e) electrophoresis

34. Based on the indicated position of the wells, the longest DNA fragment in the crime scene sample is at position

(a) 1
(b) 2
(c) 3
(d) 4
(e) 5

35. Based on the results of this forensic investigation, it is likely that the guilty culprit is

(a) Mr. Bean
(b) Bob
(c) Ray
(d) Tim
(e) Mr. Rogers

Use the diagram below to assist you in answering questions 36 to 38.

36.  Structure A contains a

(a) genetic code
(b) messenger RNA molecule
(c) single nucleotide, only
(d) small polysaccharide
(e) male gamete

37. Structure B represents

(a) a ribosome
(b) recombinant DNA
(c) transfer RNA
(d) a female gamete
(e) a rubber band

38. The technique illustrated in the diagram is known as

(a) cloning
(b) protein synthesis
(c) genetic engineering
(d) in vitro fertilization
(e) weird sex

 

 

 

 



 

 

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